PDBe 1uqr

X-ray diffraction
1.7Å resolution

Type II 3-dehydroquinate dehydratase (DHQase) from Actinobacillus pleuropneumoniae

Released:

Function and Biology Details

Reaction catalysed:
3-dehydroquinate = 3-dehydroshikimate + H(2)O. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo 12-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-dehydroquinate dehydratase Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 154 amino acids
Theoretical weight: 17.2 KDa
Source organism: Actinobacillus pleuropneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: P43877 (Residues: 1-154; Coverage: 100%)
Gene name: aroQ
Sequence domains: Dehydroquinase class II
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P212121
Unit cell:
a: 129.095Å b: 131.333Å c: 161.619Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.178 0.199
Expression system: Escherichia coli