› 1un3

X-ray diffraction
1.7Å resolution

CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T44D

Released:
DOI: 10.2210/pdb1un3/pdb
PDB entry 1un3 coloured by chain, front view.
PDB entry 1un3 coloured by chain, side view.
PDB entry 1un3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41.
Holloway DE, Chavali GB, Hares MC, Baker MD, Subbarao GV, Shapiro R, Acharya KR
Biochemistry 43 1230-41 (2004)
PMID: 14756559

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137273 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P03950 (Residues: 25-147; Coverage: 100%)
Gene names: ANG, RNASE5
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21212
Unit cell:
a: 88.398Å b: 41.533Å c: 33.761Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.223
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Generation of 2',3'-Cyclic Phosphate-Containing RNAs as a Hidden Layer of the Transcriptome.
Shigematsu et al. (2018)
8 other articles

2 mentions without citation

A feature-based approach to modeling protein-protein interaction hot spots.
Cho et al. (2009)
1 more