PDBe 1umi

X-ray diffraction
2.4Å resolution

Structural basis of sugar-recognizing ubiquitin ligase

Released:
Source organism: Mus musculus
Primary publication:
Structural basis of sugar-recognizing ubiquitin ligase.
Nat. Struct. Mol. Biol. 11 365-70 (2004)
PMID: 14990996

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
F-box only protein 2 Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 20.99 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q80UW2 (Residues: 117-297; Coverage: 61%)
Gene names: Fbs1, Fbx2, Fbxo2
Sequence domains: F-box associated region
Structure domains: Galactose-binding domain-like

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43212
Unit cell:
a: 63.806Å b: 63.806Å c: 147.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.197 0.256
Expression system: Escherichia coli