PDBe 1ujy

Solution NMR

Solution structure of SH3 domain in Rac/Cdc42 guanine nucleotide exchange factor(GEF) 6

Released:
Source organism: Homo sapiens
Entry authors: He F, Muto Y, Uda H, Koshiba S, Shirouzu M, Terada T, Kigawa T, Inoue M, Yabuki T, Aoki M, Seki E, Matsuda T, Hirota H, Yoshida M, Kobayashi N, Tanaka A, Osanai T, Matsuo Y, Ohara O, Nagase T, Kikuno R, Nagayama M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho guanine nucleotide exchange factor 6 Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.37 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15052 (Residues: 160-222; Coverage: 8%)
Gene names: ARHGEF6, COOL2, KIAA0006, PIXA
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: torsion angle dynamics
Chemical shifts: BMR11356  
Expression system: Not provided