PDBe 1ujn

X-ray diffraction
1.8Å resolution

Crystal structure of dehydroquinate synthase from Thermus thermophilus HB8

Released:

Function and Biology Details

Reaction catalysed:
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-dehydroquinate synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 348 amino acids
Theoretical weight: 37.56 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: P83703 (Residues: 1-348; Coverage: 100%)
Gene name: aroB
Sequence domains: 3-dehydroquinate synthase
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P21
Unit cell:
a: 63.403Å b: 71.787Å c: 71.636Å
α: 90° β: 99.44° γ: 90°
R-values:
R R work R free
0.203 0.202 0.236
Expression system: Escherichia coli