› › Function and Biology

Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-valine

Source organism: Agrobacterium sp.
Biochemical function: N-carbamoyl-D-amino acid hydrolase activity
Biological process: beta-alanine biosynthetic process via 3-ureidopropionate
Cellular component: not assigned

Quick links

EC 3.5.1.77: N-carbamoyl-D-amino-acid hydrolase

Reaction catalysed:
N-carbamoyl-D-amino acid + H(2)O = D-amino acid + NH(3) + CO(2)
Systematic name:
N-carbamoyl-D-amino-acid amidohydrolase
Alternative Name(s):
  • D-N-carbamoylase
  • N-carbamoyl-D-amino acid hydrolase
  • N-carbamoylase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00795
Domain description: Carbon-nitrogen hydrolase
Occurring in:
  1. N-carbamoyl-D-amino acid hydrolase
The deposited structure of PDB entry 1uf7 contains 2 copies of Pfam domain PF00795 (Carbon-nitrogen hydrolase) in N-carbamoyl-D-amino acid hydrolase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003010
Domain description: Carbon-nitrogen hydrolase
Occurring in:
  1. N-carbamoyl-D-amino acid hydrolase
IPR036526
Domain description: Carbon-nitrogen hydrolase superfamily
Occurring in:
  1. N-carbamoyl-D-amino acid hydrolase

Structure domain

CATH CATH domain
3.60.110.10
Class: Alpha Beta
Architecture: 4-Layer Sandwich
Topology: Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase
Homology: Carbon-nitrogen hydrolase
Occurring in:
  1. N-carbamoyl-D-amino acid hydrolase
The deposited structure of PDB entry 1uf7 contains 2 copies of CATH domain 3.60.110.10 (Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase) in N-carbamoyl-D-amino acid hydrolase. Showing 1 copy in chain A.
SCOP SCOP annotation
64433
Class: Alpha and beta proteins (a+b)
Fold: Carbon-nitrogen hydrolase
Superfamily: Carbon-nitrogen hydrolase
Occurring in:
  1. N-carbamoyl-D-amino acid hydrolase
The deposited structure of PDB entry 1uf7 contains 2 copies of SCOP domain 64433 (Carbamilase) in N-carbamoyl-D-amino acid hydrolase. Showing 1 copy in chain A.

Quick links