› 1uay

X-ray diffraction
1.4Å resolution

Crystal Structure of Type II 3-Hydroxyacyl-CoA Dehydrogenase from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb1uay/pdb
PDB entry 1uay coloured by chain, front view.
PDB entry 1uay coloured by chain, side view.
PDB entry 1uay coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Kunishima N, Asada Y, Yokoyama S, Kuramitsu S, Miyano M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181932 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxidoreductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 242 amino acids
Theoretical weight: 25.63 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7SIA1 (Residues: 1-242; Coverage: 100%)
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
Ligand ADN 2 x ADN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: C2221
Unit cell:
a: 78.93Å b: 94.871Å c: 113.529Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.181 0.197
Expression system: Escherichia coli

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