PDBe 1u3q

X-ray diffraction
2.4Å resolution

Crystal Structure of Estrogen Receptor beta complexed with CL-272

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Estrogen receptor beta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 240 amino acids
Theoretical weight: 27.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92731 (Residues: 261-500; Coverage: 45%)
Gene names: ESR2, ESTRB, NR3A2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS
Spacegroup: P21
Unit cell:
a: 77.167Å b: 76.646Å c: 82.8Å
α: 90° β: 111.83° γ: 90°
R-values:
R R work R free
0.242 0.227 0.279
Expression system: Escherichia coli BL21(DE3)