PDBe 1tz3

X-ray diffraction
2.9Å resolution

crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside


Function and Biology Details

Reaction catalysed:
ATP + D-fructose = ADP + D-fructose 6-phosphate. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Putative sugar kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 339 amino acids
Theoretical weight: 36.63 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Expression system: Escherichia coli
  • Canonical: Q8ZKR2 (Residues: 1-319; Coverage: 100%)
Gene name: STM4066
Sequence domains: pfkB family carbohydrate kinase
Structure domains: UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 8-BM
Spacegroup: P212121
Unit cell:
a: 135.851Å b: 54.098Å c: 89.796Å
α: 90° β: 90° γ: 90°
R R work R free
0.213 0.205 0.275
Expression system: Escherichia coli