PDBe 1tyl

X-ray diffraction
1.9Å resolution

THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE

Released:
Source organism: Homo sapiens
Primary publication:
The structure of a complex of hexameric insulin and 4'-hydroxyacetanilide.
Proc. Natl. Acad. Sci. U.S.A. 91 8851-5 (1994)
PMID: 8090735

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero 12-mer
hetero tetramer
hetero nonamer
hetero hexamer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
Insulin B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 25-54; Coverage: 35%)
Gene name: INS

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: R3
Unit cell:
a: 81.11Å b: 81.11Å c: 37.97Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 not available not available
Expression system: Not provided