PDBe 1toz

Solution NMR

NMR structure of the human NOTCH-1 ligand binding region

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurogenic locus notch homolog protein 1 Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 12.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P46531 (Residues: 411-526; Coverage: 5%)
Gene names: NOTCH1, TAN1
Sequence domains:
Structure domains: Laminin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21