PDBe 1tli

X-ray diffraction
2.05Å resolution

THERMOLYSIN (2% ISOPROPANOL SOAKED CRYSTALS)

Released:

Function and Biology Details

Reaction catalysed:
Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thermolysin Chain: A
Molecule details ›
Chain: A
Length: 316 amino acids
Theoretical weight: 34.36 KDa
Source organism: Bacillus thermoproteolyticus
UniProt:
  • Canonical: P00800 (Residues: 233-548; Coverage: 61%)
Gene name: npr
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P6122
Unit cell:
a: 93.93Å b: 93.93Å c: 130.91Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.165 0.165 0.219