PDBe 1tgr

X-ray diffraction
1.42Å resolution

Crystal Structure of mini-IGF-1(2)

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin-like growth factor I Chains: A, B
Molecule details ›
Chains: A, B
Length: 52 amino acids
Theoretical weight: 5.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05019 (Residues: 49-77, 90-110; Coverage: 29%)
Gene names: IBP1, IGF1
Structure domains: Insulin-like, subunit E

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6B
Spacegroup: I222
Unit cell:
a: 58.86Å b: 61.98Å c: 70.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.196 0.224
Expression system: Escherichia coli