PDBe 1tf0

X-ray diffraction
2.7Å resolution

Crystal structure of the GA module complexed with human serum albumin


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serum albumin Chain: A
Molecule details ›
Chain: A
Length: 572 amino acids
Theoretical weight: 65.32 KDa
Source organism: Homo sapiens
  • Canonical: P02768 (Residues: 25-596; Coverage: 97%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family
Structure domains: Serum Albumin; Chain A, Domain 1
Peptostreptococcal albumin-binding protein Chain: B
Molecule details ›
Chain: B
Length: 53 amino acids
Theoretical weight: 5.94 KDa
Source organism: Finegoldia magna ATCC 29328
Expression system: Escherichia coli
  • Canonical: Q51911 (Residues: 213-265; Coverage: 15%)
Gene name: pab
Structure domains: Albumin-binding domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2221
Unit cell:
a: 96.295Å b: 134.799Å c: 122.463Å
α: 90° β: 90° γ: 90°
R R work R free
0.251 0.249 0.295
Expression system: Escherichia coli