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Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core

Source organism: Oryctolagus cuniculus
Biochemical function: voltage-gated calcium channel activity
Biological process: calcium ion transmembrane transport
Cellular component: voltage-gated calcium channel complex

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00625
Domain description: Guanylate kinase
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
The deposited structure of PDB entry 1t3s contains 1 copy of Pfam domain PF00625 (Guanylate kinase) in Voltage-dependent L-type calcium channel subunit beta-2. Showing 1 copy in chain A.

PF12052
Domain description: Voltage gated calcium channel subunit beta domain 4Aa N terminal
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
The deposited structure of PDB entry 1t3s contains 1 copy of Pfam domain PF12052 (Voltage gated calcium channel subunit beta domain 4Aa N terminal) in Voltage-dependent L-type calcium channel subunit beta-2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000584
Domain description: Voltage-dependent calcium channel, L-type, beta subunit
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
IPR008145
Domain description: Guanylate kinase/L-type calcium channel beta subunit
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
IPR005444
Domain description: Voltage-dependent calcium channel, L-type, beta-2 subunit
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
IPR001452
Domain description: SH3 domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
IPR035605
Domain description: CACNB2, SH3 domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
IPR046937
Domain description: Voltage-dependent L-type calcium channel subunit beta-1-4, N-terminal A domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2

Structure domains

CATH CATH domains
2.30.30.40
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 Domains
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
The deposited structure of PDB entry 1t3s contains 1 copy of CATH domain 2.30.30.40 (SH3 type barrels.) in Voltage-dependent L-type calcium channel subunit beta-2. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
The deposited structure of PDB entry 1t3s contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Voltage-dependent L-type calcium channel subunit beta-2. Showing 1 copy in chain A.
SCOP SCOP annotations
52541
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
The deposited structure of PDB entry 1t3s contains 1 copy of SCOP domain 52541 (Nucleotide and nucleoside kinases) in Voltage-dependent L-type calcium channel subunit beta-2. Showing 1 copy in chain A.
50045
Class: All beta proteins
Fold: SH3-like barrel
Superfamily: SH3-domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit beta-2
The deposited structure of PDB entry 1t3s contains 1 copy of SCOP domain 50045 (SH3-domain) in Voltage-dependent L-type calcium channel subunit beta-2. Showing 1 copy in chain A.

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