PDBe 1shf

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF THE SH3 DOMAIN IN HUMAN FYN; COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SH3 DOMAINS IN TYROSINE KINASES AND SPECTRIN

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Fyn Chains: A, B
Molecule details ›
Chains: A, B
Length: 59 amino acids
Theoretical weight: 6.74 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P06241 (Residues: 84-142; Coverage: 11%)
Gene name: FYN
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 73.7Å b: 48.6Å c: 43Å
α: 90° β: 98.1° γ: 90°
R-values:
R R work R free
0.18 0.18 not available
Expression system: Not provided