PDBe 1ses

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE

Released:

Function and Biology Details

Reaction catalysed:
(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec). 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine--tRNA ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 421 amino acids
Theoretical weight: 47.88 KDa
Source organism: Thermus thermophilus
Expression system: Not provided
UniProt:
  • Canonical: P34945 (Residues: 1-421; Coverage: 100%)
Gene names: TT_C0520, serS
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 85.1Å b: 125.2Å c: 62.4Å
α: 90° β: 108.8° γ: 90°
R-values:
R R work R free
0.176 0.176 not available
Expression system: Not provided