PDBe 1s9q

X-ray diffraction
2.2Å resolution

crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen


Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Estrogen-related receptor gamma Chains: A, B
Molecule details ›
Chains: A, B
Length: 251 amino acids
Theoretical weight: 28.39 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P62509 (Residues: 229-456; Coverage: 50%)
Gene names: Err3, Esrrg, Kiaa0832, Nr3b3
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P4322
Unit cell:
a: 89.481Å b: 89.481Å c: 161.761Å
α: 90° β: 90° γ: 90°
R R work R free
0.22 0.22 0.244
Expression system: Escherichia coli BL21(DE3)