PDBe 1s6c

X-ray diffraction
2Å resolution

Crystal structure of the complex between KChIP1 and Kv4.2 N1-30

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kv channel-interacting protein 1 Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 21.76 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8R426 (Residues: 45-227; Coverage: 81%)
Gene names: Kchip1, Kcnip1
Sequence domains:
Structure domains: EF-hand
Potassium voltage-gated channel subfamily D member 2 Chain: B
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 2.97 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q63881 (Residues: 1-30; Coverage: 5%)
Gene name: Kcnd2

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: I222
Unit cell:
a: 74.744Å b: 74.487Å c: 85.41Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.245
Expression systems:
  • Escherichia coli
  • Escherichia coli BL21(DE3)