› 1rtb

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE DISPOSITION OF THYMIDYLIC ACID TETRAMER IN COMPLEX WITH RIBONUCLEASE A

Released:
DOI: 10.2210/pdb1rtb/pdb
PDB entry 1rtb coloured by chain, front view.
PDB entry 1rtb coloured by chain, side view.
PDB entry 1rtb coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A.
Birdsall DL, McPherson A
J Biol Chem 267 22230-6 (1992)
PMID: 1429575

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 44.9Å b: 74.9Å c: 44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 not available
Expression system: Not provided

Quick links

Citations

11 citation in other articles

A structural basis of the interactions between leucine-rich repeats and protein ligands.
Kobe et al. (1995)
10 more

10 mentions without citation

Caught in self-interaction: evolutionary and functional mechanisms of protein homooligomerization.
Hashimoto et al. (2011)
9 more