› 1rrm

X-ray diffraction
1.6Å resolution

Crystal Structure of Lactaldehyde reductase

Released:
DOI: 10.2210/pdb1rrm/pdb
PDB entry 1rrm coloured by chain, front view.
PDB entry 1rrm coloured by chain, side view.
PDB entry 1rrm coloured by chain, top view.
Source organism: Escherichia coli
Entry authors: Kumaran D, Swaminathan S, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
(R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141921 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactaldehyde reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 386 amino acids
Theoretical weight: 41.54 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A9S1 (Residues: 1-382; Coverage: 100%)
Gene names: JW2770, b2799, fucO
Sequence domains: Iron-containing alcohol dehydrogenase
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand ZN 2 x ZN
Ligand FE2 2 x FE2
Ligand APR 2 x APR
Ligand PGO 2 x PGO
1 modified residue:
Ligand MSE 26 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 61.766Å b: 97.527Å c: 69.514Å
α: 90° β: 113.63° γ: 90°
R-values:
R R work R free
0.193 0.193 0.211
Expression system: Escherichia coli

Quick links