PDBe 1rpt

X-ray diffraction
3Å resolution

CRYSTAL STRUCTURES OF RAT ACID PHOSPHATASE COMPLEXED WITH THE TRANSITIONS STATE ANALOGS VANADATE AND MOLYBDATE: IMPLICATIONS FOR THE REACTION MECHANISM

Released:

Function and Biology Details

Reactions catalysed:
A phosphate monoester + H(2)O = an alcohol + phosphate. 
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prostatic acid phosphatase Chain: A
Molecule details ›
Chain: A
Length: 342 amino acids
Theoretical weight: 39.69 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P20646 (Residues: 32-373; Coverage: 98%)
Gene name: Acpp
Sequence domains: Histidine phosphatase superfamily (branch 2)
Structure domains: Phosphoglycerate mutase-like

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 89.4Å b: 89.4Å c: 152Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.215 0.215 not available
Expression system: Not provided