PDBe 1rj6

X-ray diffraction
2.9Å resolution

Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV in Complex with Acetazolamide


Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Carbonic anhydrase 14 Chains: A, B
Molecule details ›
Chains: A, B
Length: 261 amino acids
Theoretical weight: 29.33 KDa
Source organism: Mus musculus
Expression system: Chlorocebus aethiops
  • Canonical: Q9WVT6 (Residues: 18-278; Coverage: 81%)
Gene names: Ca14, Car14, Catm
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Carbonic Anhydrase II

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 59.2Å b: 75.8Å c: 73.8Å
α: 90° β: 99.2° γ: 90°
R R work R free
0.207 0.207 0.253
Expression system: Chlorocebus aethiops