EC 3.1.26.3: Ribonuclease III
Reaction catalysed:
Endonucleolytic cleavage to 5'-phosphomonoester.
Systematic name:
-
Alternative Name(s):
- RNase III
- Ribonuclease 3
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)![The deposited structure of PDB entry 1rc7 contains 1 copy of Pfam domain PF00035 (Double-stranded RNA binding motif) in Ribonuclease 3. Showing 1 copy in chain E [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1rc7_2_A_Pfam_PF00035_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1rc7</span> contains 1 copy of Pfam domain <span class='highlight'>PF00035 (Double-stranded RNA binding motif)</span> in <span class='highlight'>Ribonuclease 3</span>. Showing 1 copy in chain <span class='highlight'>E [auth A]</span>.")
![The deposited structure of PDB entry 1rc7 contains 1 copy of Pfam domain PF00636 (Ribonuclease III domain) in Ribonuclease 3. Showing 1 copy in chain E [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1rc7_2_A_Pfam_PF00636_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1rc7</span> contains 1 copy of Pfam domain <span class='highlight'>PF00636 (Ribonuclease III domain)</span> in <span class='highlight'>Ribonuclease 3</span>. Showing 1 copy in chain <span class='highlight'>E [auth A]</span>.")
InterPro annotationsStructure domains
CATH domains
3.30.160.20
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Double Stranded RNA Binding Domain
Homology:
Double Stranded RNA Binding Domain
Occurring in:
![The deposited structure of PDB entry 1rc7 contains 1 copy of CATH domain 3.30.160.20 (Double Stranded RNA Binding Domain) in Ribonuclease 3. Showing 1 copy in chain E [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1rc7_2_A_CATH_3.30.160.20_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1rc7</span> contains 1 copy of CATH domain <span class='highlight'>3.30.160.20 (Double Stranded RNA Binding Domain)</span> in <span class='highlight'>Ribonuclease 3</span>. Showing 1 copy in chain <span class='highlight'>E [auth A]</span>.")
![The deposited structure of PDB entry 1rc7 contains 1 copy of CATH domain 1.10.1520.10 (Ribonuclease iii, N-terminal Endonuclease Domain; Chain A) in Ribonuclease 3. Showing 1 copy in chain E [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1rc7_2_A_CATH_1.10.1520.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1rc7</span> contains 1 copy of CATH domain <span class='highlight'>1.10.1520.10 (Ribonuclease iii, N-terminal Endonuclease Domain; Chain A)</span> in <span class='highlight'>Ribonuclease 3</span>. Showing 1 copy in chain <span class='highlight'>E [auth A]</span>.")
SCOP annotations![The deposited structure of PDB entry 1rc7 contains 1 copy of SCOP domain 54769 (Double-stranded RNA-binding domain (dsRBD)) in Ribonuclease 3. Showing 1 copy in chain E [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1rc7_2_A_SCOP_54769_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1rc7</span> contains 1 copy of SCOP domain <span class='highlight'>54769 (Double-stranded RNA-binding domain (dsRBD))</span> in <span class='highlight'>Ribonuclease 3</span>. Showing 1 copy in chain <span class='highlight'>E [auth A]</span>.")
![The deposited structure of PDB entry 1rc7 contains 1 copy of SCOP domain 69066 (RNase III catalytic domain-like) in Ribonuclease 3. Showing 1 copy in chain E [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1rc7_2_A_SCOP_69066_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1rc7</span> contains 1 copy of SCOP domain <span class='highlight'>69066 (RNase III catalytic domain-like)</span> in <span class='highlight'>Ribonuclease 3</span>. Showing 1 copy in chain <span class='highlight'>E [auth A]</span>.")