PDBe 1qz2

X-ray diffraction
3Å resolution

Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 336 amino acids
Theoretical weight: 38.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: Q02790 (Residues: 145-459)
Gene names: FKBP4, FKBP52
Heat shock protein HSP 90-beta Chains: G, H
Molecule details ›
Chains: G, H
Length: 5 amino acids
Theoretical weight: 622 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Best match: P08238 (Residues: 720-724)
Gene names: HSP90AB1, HSP90B, HSPC2, HSPCB

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 111.613Å b: 144.417Å c: 170.815Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.23 0.287
Expression systems:
  • Escherichia coli
  • Not provided