PDBe 1qre

X-ray diffraction
1.46Å resolution

A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase Chain: A
Molecule details ›
Chain: A
Length: 247 amino acids
Theoretical weight: 26.43 KDa
Source organism: Methanosarcina thermophila
Expression system: Escherichia coli
UniProt:
  • Canonical: P40881 (Residues: 1-247; Coverage: 100%)
Sequence domains:
Structure domains: Hexapeptide repeat proteins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P213
Unit cell:
a: 82.581Å b: 82.581Å c: 82.581Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.185 0.206
Expression system: Escherichia coli