PDBe 1qpj

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH STAUROSPORINE.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Lck Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 32.35 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Best match: P06239 (Residues: 231-509)
Gene name: LCK

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 61.54Å b: 69.04Å c: 73.73Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.267
Expression system: Trichoplusia ni