PDBe 1qkn

X-ray diffraction
2.25Å resolution

RAT OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH ANTAGONIST RALOXIFENE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Estrogen receptor beta Chain: A
Molecule details ›
Chain: A
Length: 255 amino acids
Theoretical weight: 28.69 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q62986 (Residues: 255-509; Coverage: 48%)
Gene names: Erbeta, Esr2, Nr3a2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P4122
Unit cell:
a: 67.55Å b: 67.55Å c: 148.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.263
Expression system: Escherichia coli