PDBe 1qg1

Solution NMR

GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH AN SHC-DERIVED PEPTIDE

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SHC-transforming protein 1 Chain: I
Molecule details ›
Chain: I
Length: 13 amino acids
Theoretical weight: 1.59 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P29353 (Residues: 423-435; Coverage: 2%)
Gene names: SHC, SHC1, SHCA
Growth factor receptor-bound protein 2 Chain: E
Molecule details ›
Chain: E
Length: 104 amino acids
Theoretical weight: 12.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62993 (Residues: 58-159; Coverage: 47%)
Gene names: ASH, GRB2
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Expression systems:
  • Not provided
  • Escherichia coli