PDBe 1qd1

X-ray diffraction
1.7Å resolution

THE CRYSTAL STRUCTURE OF THE FORMIMINOTRANSFERASE DOMAIN OF FORMIMINOTRANSFERASE-CYCLODEAMINASE.

Released:

Function and Biology Details

Reactions catalysed:
5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH(3). 
(1) 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate. (2) 5-formyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formyl- L-glutamate. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Formimidoyltransferase-cyclodeaminase Chains: A, B
Molecule details ›
Chains: A, B
Length: 325 amino acids
Theoretical weight: 35.88 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P53603 (Residues: 2-326; Coverage: 60%)
Gene name: FTCD
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200, NSLS BEAMLINE X8C
Spacegroup: P212121
Unit cell:
a: 64.31Å b: 103.84Å c: 122.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 0.213
Expression system: Escherichia coli