PDBe 1qcn

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fumarylacetoacetase Chains: A, B
Molecule details ›
Chains: A, B
Length: 421 amino acids
Theoretical weight: 47.05 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P35505 (Residues: 1-419; Coverage: 100%)
Gene name: Fah
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 64.321Å b: 110.343Å c: 67.533Å
α: 90° β: 102.38° γ: 90°
R-values:
R R work R free
0.191 0.191 0.22
Expression system: Escherichia coli