EC 1.6.5.2: NAD(P)H dehydrogenase (quinone)
Reaction catalysed:
NAD(P)H + a quinone = NAD(P)(+) + a hydroquinone
Systematic name:
NAD(P)H:quinone oxidoreductase
Alternative Name(s):
- Azoreductase
- DT-diaphorase
- Dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone)
- Diaphorase
- Flavoprotein NAD(P)H-quinone reductase
- Menadione oxidoreductase
- Menadione reductase
- NAD(P)H dehydrogenase
- NAD(P)H menadione reductase
- NAD(P)H(2) dehydrogenase (quinone)
- NAD(P)H-quinone dehydrogenase
- NAD(P)H-quinone oxidoreductase
- NAD(P)H: menadione oxidoreductase
- NAD(P)H:(quinone-acceptor)oxidoreductase
- NADH-menadione reductase
- NQO1
- Naphthoquinone reductase
- Phylloquinone reductase
- QR1
- Quinone reductase
- Reduced NAD(P)H dehydrogenase
- Reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase
- Viologen accepting pyridine nucleotide oxidoreductase
- Vitamin K reductase
- Vitamin-K reductase
- p-benzoquinone reductase
GO terms
Biochemical function:
Biological process:
- response to flavonoid
- response to hydrogen sulfide
- response to L-glutamine
- response to tetrachloromethane
- response to nitrogen compound
- negative regulation of ferroptosis
- cellular response to metal ion
- NADPH oxidation
- cellular response to hydrogen peroxide
- response to electrical stimulus
- response to ethanol
- cell redox homeostasis
- innate immune response
- positive regulation of neuron apoptotic process
- response to alkaloid
- negative regulation of apoptotic process
- vitamin K metabolic process
- vitamin E metabolic process
- negative regulation of protein catabolic process
- cellular response to oxidative stress
- response to testosterone
- response to lipopolysaccharide
- response to estradiol
- protein catabolic process
- removal of superoxide radicals
- response to amine
- response to organic cyclic compound
- response to organic substance
- response to carbohydrate
- response to hormone
- response to toxic substance
- response to xenobiotic stimulus
- response to nutrient
- synaptic transmission, cholinergic
- response to oxidative stress
- nitric oxide biosynthetic process
- xenobiotic metabolic process
- superoxide metabolic process
- ubiquinone metabolic process
- NADH oxidation
- response to ischemia
- protein polyubiquitination