PDBe 1qad

X-ray diffraction
1.8Å resolution

Crystal Structure of the C-Terminal SH2 Domain of the P85 alpha Regulatory Subunit of Phosphoinositide 3-Kinase: An SH2 domain mimicking its own substrate

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 12.62 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P23727 (Residues: 614-724; Coverage: 15%)
Gene name: PIK3R1
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX7.2
Spacegroup: P212121
Unit cell:
a: 38.68Å b: 46.92Å c: 62.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.158 0.236
Expression system: Not provided