› 1qa5

Solution NMR

MYRISTOYLATED HIV-1 NEF ANCHOR DOMAIN, NMR, 2 STRUCTURES

Released:
DOI: 10.2210/pdb1qa5/pdb
PDB entry 1qa5 coloured by chain, ensemble of 2 models, front view.
PDB entry 1qa5 coloured by chain, ensemble of 2 models, side view.
PDB entry 1qa5 coloured by chain, ensemble of 2 models, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.
Geyer M, Munte CE, Schorr J, Kellner R, Kalbitzer HR
J Mol Biol 289 123-38 (1999)
PMID: 10339411

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137592 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein Nef Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.03 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04324 (Residues: 2-57; Coverage: 27%)
Gene name: nef
Structure domains: HIV 1 nef anchor domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

13 review citations

Natively unfolded proteins: a point where biology waits for physics.
Uversky VN. (2002)
12 more

13 mentions without citation

How HIV Nef Proteins Hijack Membrane Traffic To Promote Infection.
Buffalo et al. (2019)
12 more