PDBe 1q4l

X-ray diffraction
2.77Å resolution

GSK-3 Beta complexed with Inhibitor I-5

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycogen synthase kinase-3 beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 424 amino acids
Theoretical weight: 47.08 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Best match: P49841 (Residues: 2-420)
Gene name: GSK3B

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 84.167Å b: 86.664Å c: 178.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.212 0.251
Expression system: Spodoptera frugiperda