PDBe 1q3h

X-ray diffraction
2.5Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystic fibrosis transmembrane conductance regulator Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 286 amino acids
Theoretical weight: 32.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P26361 (Residues: 389-673; Coverage: 19%)
Gene names: Abcc7, Cftr
Sequence domains: ABC transporter
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P4212
Unit cell:
a: 171.68Å b: 171.68Å c: 109.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.257
Expression system: Escherichia coli