PDBe 1py5

X-ray diffraction
2.3Å resolution

Function and Biology Details

Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
TGF-beta receptor type-1 Chain: A
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 37.1 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P36897 (Residues: 175-500; Coverage: 69%)
Gene names: ALK5, SKR4, TGFBR1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 41.829Å b: 78.111Å c: 90.686Å
α: 90° β: 90° γ: 90°
R R work R free
0.26 0.258 0.292
Expression system: Spodoptera frugiperda