PDBe 1psb

Solution NMR

Solution structure of calcium loaded S100B complexed to a peptide from N-Terminal regulatory domain of NDR kinase.


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein S100-B Chains: A, B
Molecule details ›
Chains: A, B
Length: 91 amino acids
Theoretical weight: 10.55 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
  • Canonical: P02638 (Residues: 2-92; Coverage: 99%)
Gene name: S100B
Sequence domains:
Structure domains: EF-hand
Serine/threonine-protein kinase 38 Chains: C, D
Molecule details ›
Chains: C, D
Length: 26 amino acids
Theoretical weight: 3.23 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q15208 (Residues: 62-87; Coverage: 6%)
Gene names: NDR1, STK38

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Torsion Angle Dynamics, Restrained Molecular Dynamics, Simulated Annealing,
Expression systems:
  • Escherichia coli
  • Not provided