PDBe 1prm

Solution NMR

TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proto-oncogene tyrosine-protein kinase Src Chain: C
Molecule details ›
Chain: C
Length: 64 amino acids
Theoretical weight: 7 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00523 (Residues: 77-140; Coverage: 12%)
Gene name: SRC
Sequence domains: SH3 domain
Structure domains: SH3 Domains
PROLINE-RICH LIGAND PLR1 (AFAPPLPRR) Chain: A
Molecule details ›
Chain: A
Length: 9 amino acids
Theoretical weight: 1.03 KDa
Source organism: Unidentified
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Expression systems:
  • Escherichia coli
  • Not provided