PDBe 1pmx

Solution NMR

INSULIN-LIKE GROWTH FACTOR-I BOUND TO A PHAGE-DERIVED PEPTIDE

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IGF-1 ANTAGONIST F1-1 Chain: B
Molecule details ›
Chain: B
Length: 16 amino acids
Theoretical weight: 1.88 KDa
Source organism: Synthetic construct
Expression system: Not provided
Insulin-like growth factor I Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 7.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P05019 (Residues: 49-118)
Gene names: IBP1, IGF1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS, SIMULATED ANNEALING
Expression systems:
  • Not provided
  • Escherichia coli