PDBe 1pmu

X-ray diffraction
2.7Å resolution

The crystal structure of JNK3 in complex with a phenantroline inhibitor

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 10 Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: P53779 (Residues: 40-401)
Gene names: JNK3, JNK3A, MAPK10, PRKM10, SAPK1B

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 62.401Å b: 62.377Å c: 98.119Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.218 0.285
Expression system: Escherichia coli BL21(DE3)