PDBe 1pkw

X-ray diffraction
2Å resolution

Crystal structure of human glutathione transferase (GST) A1-1 in complex with glutathione


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glutathione S-transferase A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 25.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P08263 (Residues: 1-222; Coverage: 100%)
Gene name: GSTA1
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand GSH 2 x GSH
1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: C2
Unit cell:
a: 99.204Å b: 90.498Å c: 51.334Å
α: 90° β: 93.37° γ: 90°
R R work R free
0.157 0.151 0.208
Expression system: Escherichia coli