PDBe 1pkg

X-ray diffraction
2.9Å resolution

Structure of a c-Kit Kinase Product Complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mast/stem cell growth factor receptor Kit Chains: A, B
Molecule details ›
Chains: A, B
Length: 329 amino acids
Theoretical weight: 37.55 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P10721 (Residues: 549-935; Coverage: 35%)
Gene names: KIT, SCFR
Structure domains:

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P21212
Unit cell:
a: 92.667Å b: 116.458Å c: 60.066Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.225 0.311
Expression system: Spodoptera frugiperda