PDBe 1pk5

X-ray diffraction
2.4Å resolution

Crystal structure of the orphan nuclear receptor LRH-1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear receptor subfamily 5 group A member 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 248 amino acids
Theoretical weight: 28.73 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P45448 (Residues: 313-560; Coverage: 44%)
Gene names: Lrh1, Nr5a2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 34.775Å b: 127.542Å c: 53.213Å
α: 90° β: 91.72° γ: 90°
R-values:
R R work R free
0.215 0.208 0.235
Expression system: Escherichia coli