PDBe 1pht

X-ray diffraction
2Å resolution

PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN, RESIDUES 1-85

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of P13K SH3 domain at 20 angstroms resolution.
J. Mol. Biol. 257 632-43 (1996)
PMID: 8648629

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 85 amino acids
Theoretical weight: 9.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P27986 (Residues: 1-85; Coverage: 12%)
Gene names: GRB1, PIK3R1
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 47Å b: 47Å c: 92.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.223 0.258
Expression system: Escherichia coli BL21(DE3)