Function and Biology Details
Reaction catalysed:
2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H(2)O = ribonucleoside diphosphate + thioredoxin
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ribonucleotide reductase large subunit, C-terminal
- Ribonucleotide reductase, class I, alpha subunit, C-terminal
- Ribonucleotide reductase large subunit, N-terminal
- Ribonucleoside-diphosphate reductase large subunit
- Ribonucleotide reductase N-terminal
- Ribonucleotide reductase, class 1b, subunit NrdE
- Ribonucleotide reductase R1 subunit, N-terminal
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170677 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonucleoside-diphosphate reductase 2 subunit alpha
Molecule details ›
Chain: A
Length: 714 amino acids
Theoretical weight: 80.69 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 714 amino acids
Theoretical weight: 80.69 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q08698 (Residues: 1-714; Coverage: 100%)
Sequence domains:
- Ribonucleotide reductase N-terminal
- Ribonucleotide reductase, all-alpha domain
- Ribonucleotide reductase, barrel domain
