Function and Biology

Fitting of gp5 in the cryoEM reconstruction of the bacteriophage T4 baseplate

EC 3.2.1.17: Lysozyme

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl- D-glucosamine residues in chitodextrins.
Comments:
Systematic name:
Peptidoglycan N-acetylmuramoylhydrolase
Alternative Name(s):
  • 1,4-N-acetylmuramidase
  • N,O-diacetylmuramidase
  • L-7001
  • PR1-lysozyme
  • Globulin G
  • Globulin G1
  • Lysozyme g
  • Mucopeptide N-acetylmuramoylhydrolase
  • Mucopeptide glucohydrolase
  • Muramidase

Sequence families

Pfam Protein families (Pfam)
PF06715
Domain description: Gp5 C-terminal repeat (3 copies)
Occurring in:
  1. Baseplate central spike complex protein gp5
3 copies of Pfam domain PF06715 (Gp5 C-terminal repeat (3 copies)) in Baseplate central spike complex protein gp5 in PDB 1pdl.

PF06714
Domain description: Gp5 N-terminal OB domain
Occurring in:
  1. Baseplate central spike complex protein gp5
1 copy of Pfam domain PF06714 (Gp5 N-terminal OB domain) in Baseplate central spike complex protein gp5 in PDB 1pdl.

PF00959
Domain description: Phage lysozyme
Occurring in:
  1. Baseplate central spike complex protein gp5
1 copy of Pfam domain PF00959 (Phage lysozyme) in Baseplate central spike complex protein gp5 in PDB 1pdl.

InterPro InterPro annotations
IPR001165
Domain description: T4-type lysozyme
Occurring in:
  1. Baseplate central spike complex protein gp5
IPR010609
Domain description: Gp5, C-terminal
Occurring in:
  1. Baseplate central spike complex protein gp5
IPR009590
Domain description: Protein Gp5, N-terminal OB-fold domain
Occurring in:
  1. Baseplate central spike complex protein gp5
IPR023347
Domain description: Lysozyme domain superfamily
Occurring in:
  1. Baseplate central spike complex protein gp5
IPR023346
Domain description: Lysozyme-like domain superfamily
Occurring in:
  1. Baseplate central spike complex protein gp5
IPR002196
Domain description: Glycoside hydrolase, family 24
Occurring in:
  1. Baseplate central spike complex protein gp5

Structure domain

SCOP SCOP annotation
103676
Class: Low resolution protein structures
Fold: Bacteriophage T4 3D cryo-EM reconstruction
Superfamily: Bacteriophage T4 3D cryo-EM reconstruction
Occurring in:
  1. Baseplate central spike complex protein gp5
1 copy of SCOP domain 103676 (Bacteriophage T4 3D cryo-EM reconstruction) in Baseplate central spike complex protein gp5 in PDB 1pdl.