PDBe 1p7m

Solution NMR

SOLUTION STRUCTURE AND BASE PERTURBATION STUDIES REVEAL A NOVEL MODE OF ALKYLATED BASE RECOGNITION BY 3-METHYLADENINE DNA GLYCOSYLASE I

Released:

Function and Biology Details

Reaction catalysed:
Hydrolysis of alkylated DNA, releasing 3-methyladenine. 
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-3-methyladenine glycosylase 1 Chain: A
Molecule details ›
Chain: A
Length: 187 amino acids
Theoretical weight: 21.14 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P05100 (Residues: 1-187; Coverage: 100%)
Gene names: JW3518, b3549, tag
Sequence domains: Methyladenine glycosylase
Structure domains: Hypothetical protein; domain 2

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli