PDBe 1p4o

X-ray diffraction
1.5Å resolution

Structure of Apo unactivated IGF-1R KInase domain at 1.5A resolution.

Released:
Source organism: Homo sapiens
Primary publication:
Structure of apo, unactivated insulin-like growth factor-1 receptor kinase at 1.5 A resolution.
Acta Crystallogr. D Biol. Crystallogr. 59 1725-30 (2003)
PMID: 14501110

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin-like growth factor 1 receptor beta chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 322 amino acids
Theoretical weight: 36.66 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P08069 (Residues: 973-1294; Coverage: 24%)
Gene name: IGF1R
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 52.95Å b: 85.56Å c: 78.88Å
α: 90° β: 99.1° γ: 90°
R-values:
R R work R free
0.209 0.209 0.236
Expression system: Spodoptera frugiperda