PDBe 1ov3

X-ray diffraction
1.8Å resolution

Structure of the p22phox-p47phox complex


Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer (preferred)
hetero octamer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neutrophil cytosol factor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P14598 (Residues: 156-285; Coverage: 33%)
Gene names: NCF1, NOXO2, SH3PXD1A
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Flavocytochrome b558 alpha polypeptide Chains: C, D
Molecule details ›
Chains: C, D
Length: 18 amino acids
Theoretical weight: 2 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P21212
Unit cell:
a: 132.66Å b: 57.81Å c: 45.17Å
α: 90° β: 90° γ: 90°
R R work R free
0.232 0.229 0.275
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided